Mpox is an exotic infectious disease caused by the Mpox virus. The disease was first identified in laboratory monkeys, thus earning its name, but in its natural state, it seems to infect rodents more than primates. A fever, headache, muscle pains, swollen lymph nodes, and fatigue are the first symptoms in humans. After this, a rash forms with blisters and crusts. Symptoms typically appear 7 to 14 days after exposure. In most cases, symptoms last 2 to 4 weeks. Children, pregnant women, and people with suppressed immune systems are at greater risk of severe cases.
Human Monkeypox – Epidemiology, Clinical Characteristics, Diagnosis, and Prevention
The human monkeypox virus, which belongs to the genus Orthopoxvirus of the family Poxviridae, is a DNA virus.
A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core.
The UK Health Security Agency (UKHSA) has today published its Pathogen Genomics Strategy, laying out a 5 year plan for the organization's role in the wider delivery of pathogen genomics to prepare for and respond to infectious disease threats to public health.
The effectiveness of the combination of current preventive responses against monkeypox (Mpox).
The global prevalence and regional differences in the intention to receive the monkeypox.
Delivering the two-dose mpox vaccine, called JYNNEOS, in smaller than the usual FDA-approved doses, and by injection between layers of the skin rather than by the standard route under the skin, produced a detectable immune response, a new study shows.
Scoping review in "Pediatric Research" examines the rise of pediatric viral diseases in the 21st century and underscores the importance of a One Health approach, integrating human, animal, and ecosystem health, to combat these emerging and re-emerging infectious threats effectively.
Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.
The stability of the monkeypox (Mpox) virus in various surroundings and bodily fluid.
This week, while KFF Health News' "What the Health?" takes a break, here’s an encore of a favorite episode this year: Host and chief Washington correspondent Julie Rovner leads a rare conversation with the current and two former secretaries of Health and Human Services.
The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.
In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.
Researchers developed a point-of-care assay for the rapid detection of mpox virus.
More than 43 years ago, many Chinese residents were vaccinated with the vaccinia virus Tiantan strain (VTT) to protect them from smallpox infection.
Monkeypox (mpox) is a zoonotic disease caused by the mpox virus (MPXV) that has been primarily limited to Central and West African nations since its discovery.
The monkeypox (mpox) virus has caused worldwide transmission since its initial report in England in early May 2022.
A new study published today shows the number of sexual partners we have changes as we age – and there are some surprising results.
Researchers elucidated monkeypox's (mpox) epidemiological and clinical features.
Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.
The history of using human challenge trials in developing vaccines.
The UK Health Security Agency (UKHSA) has today unveiled its world-leading Vaccine Development and Evaluation Centre (VDEC), which is building on its pandemic legacy and helping develop life-saving new vaccines for the UK and worldwide.