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Researchers discover non-opioid therapeutic for relieving neuropathic pain

Among the most difficult types of pain to alleviate is neuropathic pain, pain that is usually caused by damage to nerves in various body tissues, including skin, muscle and joints.

31 Jan 2024

CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Joseph Parisi as US Director of Sales. In his new role, Joe will lead the expansion of the Company’s sales and support activities for the US market to address the growing demand for new alternative methodologies (NAMs) in preclinical drug discovery.

From CN Bio Innovations Limited 31 Jan 2024

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering from respiratory disease, today announced that it has closed a £26 million ($33.1 million USD) Series B follow-on financing round, led by Panakes Partners.

From Enterprise Therapeutics Ltd 31 Jan 2024

Ancient genomes unearth degenerate transposable elements in human DNA

The human genome, an intricate tapestry of genetic information for life, has proven to be a treasure trove of strange features. Among them are segments of DNA that can "jump around" and move within the genome, known as "transposable elements" (TEs).

30 Jan 2024

Study unmasks secrets of glioma's invasive margins

High-grade gliomas are cancerous tumors that spread quickly in the brain or spinal cord.

30 Jan 2024

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

Dr. Jeannine Gerhardt, an assistant professor of stem cell biology in obstetrics and gynecology and in reproductive medicine at Weill Cornell Medicine, has received a five-year, $2.1 million grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, for the study of repetitive DNA and RNA sequences and the mechanisms by which they cause cell dysfunction and diseases.

30 Jan 2024

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

30 Jan 2024

Cambridge scientists discover how fasting turns up the body's natural inflammation fighter

Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation – a potentially damaging side-effect of the body's immune system that underlies a number of chronic diseases.

30 Jan 2024

New drug kills tumor cells by triggering a deadly calcium storm

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

MGI Unveils Comprehensive Expansion of Automation Product Lines for Life Science and Healthcare Research

MGI Tech Co., Ltd. (referred to as MGI), a leading provider of cutting-edge tools and technology for life science and healthcare research, today announced a strategic expansion of its automation product lines.

From MGI 30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

Gene variant linked to increased miscarriage risk through disrupted chromosome pairing

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

29 Jan 2024

Study sheds new light on how obesity affects fat cells' mitochondria

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.

29 Jan 2024

Scientists discover key pathway linking brain's habit center and motor learning region

Researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc).

29 Jan 2024

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

Gene activity plays key role in immune cell production, study shows

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19.

27 Jan 2024

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

Scientists at La Jolla Institute for Immunology (LJI) have found direct evidence that exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2. In fact, prior exposure to a common cold coronavirus appears to partially protect mice from lung damage during a subsequent SARS-CoV-2 infection.

27 Jan 2024

HIV virus found to possess hidden transport ability

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

Biohybrid robot makes sharp rotations with lab-grown muscles

Compared to robots, human bodies are flexible, capable of fine movements, and can convert energy efficiently into movement.

27 Jan 2024

Life Science News

Researchers discover non-opioid therapeutic for relieving neuropathic pain

CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Ancient genomes unearth degenerate transposable elements in human DNA

Study unmasks secrets of glioma's invasive margins

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Cambridge scientists discover how fasting turns up the body's natural inflammation fighter

New drug kills tumor cells by triggering a deadly calcium storm

MGI Unveils Comprehensive Expansion of Automation Product Lines for Life Science and Healthcare Research

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Gene variant linked to increased miscarriage risk through disrupted chromosome pairing

Study sheds new light on how obesity affects fat cells' mitochondria

Scientists discover key pathway linking brain's habit center and motor learning region

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Gene activity plays key role in immune cell production, study shows

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

HIV virus found to possess hidden transport ability

Biohybrid robot makes sharp rotations with lab-grown muscles

How do mass spectrometry and omics impact neurosciences?

Meet Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

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